The 35 boxes in this series cover the years 1898-1961. The Messrs. Rockefeller, Sr. and Jr., Abby Aldrich Rockefeller, Abby Rockefeller Mauze, the five brothers, and their spouses are all represented in this series. Mr. Rockefeller, Jr., John D. 3rd, and Laurance S. Rockefeller are have the most connection to thse records.

The Boards represented in this series are the most important philanthropies that have been developed from the Rockefeller fortune: the Bureau of Social Hygiene; the China Medical Board of the Rockefeller Foundation and its successor, the China Medical Board, Inc.; the Davison Fund; the General Education Board; the Laura Spelman Rockefeller Memorial; the Rockefeller Brothers Fund; the Rockefeller Foundation; the Rockefeller Institute for Medical Research (now known as Rockefeller University); the Rockefeller Sanitary Commission; the Sealantic Fund; and the Spelman Fund of New York.

Contains the correspondence and reports of the International Health Board/International Health Division (IHB/D) of the Rockefeller Foundation, including the Rockefeller Institute Virus Laboratories.