The records of the Foundation Center span the years 1922-2004, with the majority of the records dating from the mid-1950s, when the Center was created, to the early 1990s. Most of the material prior to 1956 comes from F. Emerson Andrews, the first president of the Foundation Center. Prior to 1956, Andrews had worked at the Russell Sage Foundation, and much of the correspondence relating to the Foundation Center was addressed to him there.

Primarily documents appropriations, with a small selection of financial records and audiovisual materials.

Contains the correspondence and reports of the International Health Board/International Health Division (IHB/D) of the Rockefeller Foundation, including the Rockefeller Institute Virus Laboratories.