This series consists of more than 80 volumes of aggregated factual material on both national and state issues. The Issue Books contain statements and press releases issued by the Gubernatorial Press Office in response to important political and policy issues, as well as other substantive material. Governor Rockefeller also had many experts write background papers on various subjects relevant to the two campaigns. In most cases, these papers are coupled with summary papers or supporting memoranda for Governor Rockefeller to assist him with the formulation of a position on the issue.

Prior to his election as Governor of New York in November 1958, Nelson A. Rockefeller maintained an office at Rockefeller Center in Manhattan. To separate his work as Governor from his private activities, Governor Rockefeller established an office in Manhattan at 22 West 55th Street. This became known as the New York Office, to distinguish it from the Governor's office in the state capitol building in Albany. Governor Rockefeller was the first governor to maintain a permanent office in New York City. In general, Governor Rockefeller was in Albany only when the state legislature was in session or on special occasion. The management of his public duties was largely undertaken from the New York Office.

This series contains a small portion of the files of Hugh Morrow, who served as a speech writer and special assistant to Gov. Nelson A. Rockefeller from November 1959 and was appointed Director of Communications on February 4, 1969.

Although the acronym DNA may have stood for Definitive News Analysis, no corroboration has been found in the written record. The staff of DNA were on Rockefeller's personal payroll.