Central Files is composed chiefly of correspondence sent and received between Columbia University administrators and other University officers, faculty, and trustees, as well as correspondence sent and received between University administrators and individuals and organizations from outside the university.

An artificial collection comprised of correspondence, diaries, lecture notes, essays, administrative documents, minutes, and other documents related to Columbia University. Materials were created by or for students, alumni, faculty, administrators, staff, trustees, and honorary degree recipients.

The materials that comprise the Historical Biographical Files have been collected and added to from a variety of sources over the years by current and previous staff. The files consist of materials related to people who have a connection to the University whether as student, alumni, administrator, faculty, staff, guest lecturer, or honorary degree recipient. Materials generally consist of newspaper and magazine clippings, press releases, programs, ephemera, printed matter, lists, reports, and pamphlets.

The Historical Photo Collection contains images of persons, events, and activities associated with Columbia College (1754-1896) and Columbia University (1896-).