Isaac Edwards (1819-1879) was born in South Corinth, New York. He married Anna (1826-1907), a granddaughter of Ezra Ames, and had three children who survived to adulthood. Isaac eventually became a professor at the Albany Law School, served on the Albany Board of Public Instruction, and became a member of the Congregational Church. This collection includes clippings, essays, photographs, and other Edwards family-related materials.

Thomas Worth Olcott (1795-1880) was born in Hudson, Columbia County, New York, to Josiah and Carolina Worth Olcott. Olcott eventually became president of the Mechanics and Farmer Bank in Albany, New York, and served on the boards of the Albany Law School and the Dudley Observatory, among others. This collection contains estate records, correspondence, newspaper clippings, bills, account books, photographs, scrapbooks, and genealogical information.