This collection documents the personal and political life of Herbert H. Lehman, who served as lieutenant governor, governor, and senator of New York, and as director-general of the United Nations Relief and Rehabilitation Administration.

The collection consiste of correspondence, memoranda, reports, bulletins, clippings, photographs, awards, and printed material. The files, arranged by genre and topic and reflect her philanthropic and legislative work in the areas of health, specifically cancer, heart disease, and mental health. Her civic and legislative work is covered in detail, as well as her private interests and activities.