The Coalition to Prevent Lead Poisoning collection is comprised of two main series. The first series, Organizational Files, contains correspondence, meeting minutes and other papers related to the administration of the organization and its subcommittees during the years 2000-2004. The second series, Outreach, holds content related to CPLP's work in the community, on projects, and applying for grants during the years 2000-2004. In addition to manuscripts, the Outreach series also includes a CD-ROM for which CPLP was a partner, as well as a t-shirt and posters. A 2013 accrual to the collection consists of minutes, initatives, correspondence, New York State Advisory Council on Lead Poisoning Prevention material, reports, data, articles and clippings, floppy discs, and CDs (1999-2013). The Websites series (2016-ongoing) contains archived websites created by or about the organization.

The collection documents collaborative efforts within the religious community to meet human need, achieve mutual understanding, and work for social justice. Concerns addressed have included: hunger, poverty, housing, public education, religious education, family supports, political empowerment, criminal justice, community organization, refugee resettlement, racial justice, and police-community relations.

The Louise McIntosh Slaughter congressional papers, 1974-2018, comprise her entire career, reflecting committee and legislative work, including her interactions with staff members, other politicians, business executives, other stakeholders, and New York constituents. From 1971 to 2018 she participated in several efforts to improve communities through advocacy and leadership; the collection contains the documents produced during those years, including newspapers clippings, campaign materials, correspondence, press releases, state and federal reports, staff briefs, and the reference and research files. As much as this material might be gleaned to reproduce Slaughter's work and politics, this collection also documents the varied resources and research materials compiled by her staff members (chief of staff, legislative aides, etc.) to inform her about the issues and events of the day. The staffers' files are revealed mostly in the briefing books—generally include correspondence between Slaughter and her colleagues, newspaper clippings on closely linked topics and events, printed materials accessed from online sources like LexisNexis, fact sheets, copies and drafts of bills, and handwritten notes and peer reviewed journal articles.

The Rocky Simmons photographs (1920s-2008) are comprised of photographs originally assembled by Simmons in an album, plus additional materials donated by his children and family. The photos feature Simmons, his family and friends, and various locations central to his life. It also contains photographs he took as a professional photographer, featuring local events, weddings, musicians, sports teams, beauty contests, award ceremonies, and new businesses. The photographs are a unique window on the lives of Rochester's African American community at mid-20th century.

This collection includes reports with mounted photographs on the accomplishments of 4th-6th for 1939-1941.