A true pioneer in the area of women's rights, Elizabeth Blackwell was the first female physician in the United States. This collection primarily consists of her letters to close, personal friend Barbara Leigh Smith, later Barbara Bodichon. Also included are a few letters to Bodichon from Bessie Parkes, Dr. Emily Blackwell, and Elizabeth Whitehead.

This collection contains the papers of Cephas Breed, who graduated from Geneva Medical College in 1850. The collection has two series: Writings and Correspondence.

This collection contains the papers of Clara H. Gregory, who graduated from the Syracuse University College of Medicine in 1912. The collection has two series, Photographs and Printed Materials.

This collection contains the papers of Ellen C. Jacobsen, who was the first female instructor in the Department of Medicine and a Professor of Medicine and Psychiatry at SUNY Upstate Medical University. The collection has six series: Printed Materials, Writings, Photographs, Correspondence, Dean Search, and Subject Files.

This collection contains the papers of Mary D. Burnham, who was a Deaconess, Director of the Women’s Auxiliary of the Diocese of Central New York, founder of the Dakota League, and live-in House Mother, Superintendent, and Treasurer of Current Receipts for the House and Hospital of the Good Shepherd in Syracuse. The collection has three series: Printed Materials, Photographs, and Writings.