The Adam Clark Works Papers contain correspondence from his family and friends. Also included are diaries belonging to Adam Clark Works, his first wife, Mrs. Elida I. (Van Sickle) Works, his second wife, Mrs. Ellen (Mihill) Works, his daughter, Ruth Elida Works, and his brother, George Washington William Works. The collection also contains memorabilia, photographs and a china figurine, "Three O'Clock in the Morning." The bulk of his papers are from the 1860's. The family correspondence includes letters from his mother, Mrs. Julia (Coolidge) Works Crouch, his brothers, George Washington William Works, Robert Miller Works, Obadiah Works, his halfbrothers, James Chesterfield Crouch, Benjamin F. Crouch, and his uncle, George Griswold, who raised him after his father, George W. Works, died in 1839. The collection includes courtship and marriage letters, from both wives of Adam Clark Works. His first wife, Elida, died in 1869 after a prolonged illness. Her letters are filled with descriptive detail concerning methods of medical treatment at the Castile Water Cure Sanatorium in 1868. Adam Clark Works' in-laws, Mary and Henry C. C. Van Sickel (or Van Sickle), referred to as "Ma" and "Pa," and the Rev. Norris and Mellissa (Lamson) Mihill (or Mihills) carried on an extensive correspondence with him. The sisters of his second wife, Ellen, Mrs. Emma (Mihill) Marsh and Mrs. Caroline (Mihill) Lengfeld also wrote often. Adam Clark Works' correspondence also includes letters from many friends. Several were from former students and teaching acquaintances. The Rev. Herbert Franklin Fisk, President of Genesee Wesleyan Seminary (1868-72) and Principal of the Preparatory School at Northwestern University wrote frequently. Another close friend that he corresponded with throughout his adult life was James M. Hodge, a professor of natural science at Fort Edward Collegiate Institute, Fort Edward, N.Y. and later a partner in Ogelsby and Hodge, Plumbers, Gas & Steam Fitters of Philadelphia, Pennsylvania. He also corresponded with Joel Dorman Steele (1836-1886), author of several scientific and historical books. Of special interest are the letters from Robert H. Skinner, which give a detailed account of the Civil War from his enlistment in the 77th Regiment, N.Y. Volunteers, Company D, from November 7, 1861 until his release on March 12, 1863. Lt. Skinner's letters describe his company's march to Washington, the camp conditions, Army supplies, military engagements, medical treatment of the wounded, and the attitude of the men toward the war.

The collection includes Civil War letters written by Albert B. Williams to his parents, and miscellaneous papers

This collection is comprised of material during the time Sutermeister served as Captain of the 11th battery of the Indiana Light Artillery. It includes orders he received; receipts and invoices of supplies and muster rolls.

The Atwater Family Papers includes two series: First Five Generations, 1787-1960, and letters sent to Frances Marsh Washburn, 1914-1959. The first series consists of letters, diaries, memoranda, reminiscences and notes that span from the eighteenth through the twentieth centuries and document the lives of five generations of family members, who were connected to Rochester, New York. Specifically, the collection includes reminiscences from Lyman Barker Langworthy, which date from 1701-1869. There are fourteen typed transcriptions of letters sent to and from Stephen Atwater, that describe family matters and a property title despute. These letters date from 1844-1855. There is an 1892 memorandum from Mary Weaver Atwaterood regarding her furniture. There are also five deeds from William Langworthy for property bought in Seneca Falls and in Rochester, which are dated from 1851-1860. Ann Elizabeth Langworthy's will, dated September 2, 1875, is also in the collection. There are letters, documents, reminiscences, and a diary from Edward Weaver Atwater from his time serving in the Union Army during the Civil War, 1861-1863. There is one letter that Fanny Ann Langworthy sent to her older son, William Langworthy Atwater on January 25, 1885. Included in the collection are also six letters sent to Richard Mead Atwater from his attorney, Safford E. North, November 19-December 10, 1910 regarding purchase of his stock in Johnston Harvester Company by Massey Harris County Limited. There are twelve photocopies of letters from the American painter, Ogden Wood, which were mostly written to Richard's wife, Abby, from October 19, 1907-August 13, 1912. There are letters, diaries, reminiscences from Alice M. Atwater dating from 1894-1916. Included are also letters from William Langworthy Atwater written to his father while he worked as a clerk in the Manila Ordnance Depot, October 4, 1901-January 22, 1904. There are essays written during Edward Congdon Atwater's years as a student at the University of Rochester. Also included in the collection are letters and reminiscences from Frances Atwater Clapp that range in date from 1902-1954. There are also notes taken from family bibles and diaries, as well as letters and an affidavit from James Peabody Marsh, 1908-1930. There are a number of letters sent to and from Rowena Marsh Washburn Atwater, as well as selections of her writings. There are letters sent to and from Edward Perrin Atwater as well as letters from Julian P. Atwater.

The collection contains about 200 letters written while Charles C. Brown was with the 13th N.Y. Volunteers (1861-1863) and the 22nd N.Y. Cavalry (1864-1865). The letters represent a long and detailed record of Brown's thoughts, observations, and actions while engaged in the War for Union. Most of the letters were written to his sister Caroline (Mrs. William Van Kleek Lansing of Rochester) or to Sarah Pierrepont Brown of New York City, whom he married in June 1863. Among those frequently mentioned in the letters were William (Caroline's husband) and Charlie and Frances (Mr. and Mrs. Charles Pelletreau of Brooklyn). She was Sarah's half-sister.

Civil War letters from Charles Post, Captain of the U.S. transport steamer T. V. Arrowsmith, to his wife Amelia and daughter Emily, describing his voyage from New York to Washington, and an encounter with the Merrimac.

Collection contains two carte de visite albums of soldiers, politicans, and members of the Presidential cabinet during the American Civil War. Both the Union and the Confederacy are represented. All images are labeled with the name of the person depicted. Both albums appear to be compiled by the same person.

The Eastwood-Bigelow Family Papers includes letters written to and from the Eastwood-Bigelow family members and friends, and are chiefly personal in nature. Included are letters written by Albert Bigelow Paine and Lewis Nathaniel Chase, as well as letters written about the Civil War and trips to California and Europe. Also in the collection are family financial papers, diaries, account books, invitations and calling cards, photographs, newspaper clippings, literary items and recipes.

The Edward Walter Clark Papers are housed in 2 boxes. Box 1 contains the correspondence of Edward W. Clark and the Clark family, including Edward's parents Hiram and Susan (Reed) Clark, his brothers Charles V. Clark (b.1849) and George H. Clark (b.1855), and various other family members. Edward's letters are written in an attractive and legible hand, and reflect his personal experiences while serving in the Navy. Other letters include a recommendation from the superintendent of schools of Rochester, NY, naval assignments, and condolences to the Clark family from Navy personnel.

The Bartlett Family Papers span the years from 1733 to 1924, with the bulk of the collection falling into the thirty-year period from 1832 to 1862. The papers consist of 4 boxes containing a total of approximately 510 items, of which 360 items are letters and approximately 150 items are manuscript materials including family related manuscripts, financial and legal materials, and miscellaneous items of printed ephemera. The collection contains a significant amount of material related to the medical career of Elisha Bartlett from 1832 to 1855, and the activities of Walter Otis Bartlett, Captain 1st Rhode Island Artillery, in the Civil War during 1861 to 1862. The collection also contained some printed pamphlet materials relating to Elisha Bartlett which were removed for cataloguing purposes. See register below for a listing of these printed materials.