The Lit-Mus - short for "Literary" and "Music" -- Study Club is an on-going African American women's study group that originated in Buffalo in 1922. It was founded by Florence Jackson Lee, Amelia Anderson and Ora Lewis Anderson in the hopes of fulfilling its mission to study topics in the arts, humanities and social sciences that would enable the club's women to improve their community. It became part of the Empire State Federation of Women's Clubs as well as an affiliate of the National Association of Colored Women's Clubs. In 1928, the Study Club introduced Negro History Week to Buffalo. The Club maintains a scholarship fund that has assisted many local students with their education and supports many local charities. It has also enabled the community to have greater access to African American literature and has donated books to libraries and schools. In order to preserve the records of the Club, it was deemed advisable to house them in the Special Collections area of the Buffalo State College's E.H. Butler Library.

The Lit-Mus Study Club collection houses historical information, activities, correspondence, ephemera, printed material, subject files, and records of the organization from its founding in the 1920s (bulk, 1930s-1980s). There is significant ancillary material which highlights the activities and functions of the Empire State Federation of Women's Clubs, Inc., and other similar state- and nationwide (primarily women's) clubs and organizations.